Statins for the primary prevention of cardiovascular disease: an overview of systematic reviews
نویسندگان
چکیده
منابع مشابه
Statins for Primary Prevention of Cardiovascular Disease.
The US Preventive Services Task Force has recently recommended the use of statins in primary prevention of cardiovascular disease in adults. Doubts remain as to whether this approach is really cost-effective, and additional drawbacks include the increasing burden of potential side effects and incremental costs due to laboratory monitoring.
متن کاملStatins for the primary prevention of cardiovascular disease.
BACKGROUND Reducing high blood cholesterol, a risk factor for cardiovascular disease (CVD) events in people with and without a past history of CVD is an important goal of pharmacotherapy. Statins are the first-choice agents. Previous reviews of the effects of statins have highlighted their benefits in people with CVD. The case for primary prevention was uncertain when the last version of this r...
متن کاملStatins for the Primary Prevention of Cardiovascular Disease in Women
In this issue of Circulation, Mora et al demonstrate for the first time that statins are effective for the primary prevention of cardiovascular events in women.1 Under a prespecified analysis, the authors examined sex-specific outcomes in JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin), which enrolled 6801 women 60 years old and 11 001...
متن کاملStatins for the primary prevention of cardiovascular disease in women?
In this issue of Circulation, Mora et al demonstrate for the first time that statins are effective for the primary prevention of cardiovascular events in women.1 Under a prespecified analysis, the authors examined sex-specific outcomes in JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin), which enrolled 6801 women 60 years old and 11 001...
متن کاملAspirin for prophylactic use in the primary prevention of cardiovascular disease and cancer: a systematic review and overview of reviews.
BACKGROUND Prophylactic aspirin has been considered to be beneficial in reducing the risks of heart disease and cancer. However, potential benefits must be balanced against the possible harm from side effects, such as bleeding and gastrointestinal (GI) symptoms. It is particularly important to know the risk of side effects when aspirin is used as primary prevention--that is when used by people ...
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ژورنال
عنوان ژورنال: BMJ Open
سال: 2019
ISSN: 2044-6055,2044-6055
DOI: 10.1136/bmjopen-2018-023085